Enhanced skeletal muscle arteriolar reactivity to angiotensin II after recovery from ischemic acute renal failure
نویسندگان
چکیده
Department of Cellular and Integrative Physiology, Indiana University, Indianapolis, IN 46202 Department of Physiology, Medical College of Wisconsin, Milwaukee WI, 53226 Center for Interdisciplinary Research in Cardiovascular Sciences, Department of Physiology and Pharmacology, West Virginia University School of Medicine, Morgantown, WV, 26506 Mailing Address and correspondence to: David P. Basile, Ph.D. Department of Cellular and Integrative Physiology Indiana University School of Medicine 635 Barnhill Drive MS 334 Indianapolis, IN 46202 Tel: 317-278-1565 Fax: 317-274-3318 [email protected] Abbreviated title: Peripheral vascular reactivity following ARF
منابع مشابه
Enhanced skeletal muscle arteriolar reactivity to ANG II after recovery from ischemic acute renal failure.
In addition to the long-term renal complications, previous studies suggested that after acute renal failure (ARF), rats manifest an increased pressor response to an overnight infusion of ANG II. The present study tested whether recovery from ARF results in alterations in sensitivity to the peripheral vasculature. ARF was induced in Sprague-Dawley rats by 45 min of bilateral renal ischemia and r...
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The objective of this study was to determine the contribution of renal nerves to the enhanced afferent arteriolar reactivity observed in angiotensin II (Ang II)-induced hypertension. Uninephrectomized Sprague-Dawley rats were divided into four groups: sham rats, renal-denervated rats, Ang II-infused (at 40 ng/min for 13 days) rats, and Ang II-infused+renal-denervated rats. With the use of an im...
متن کاملInteractive nitric oxide-angiotensin II influences on renal microcirculation in angiotensin II-induced hypertension.
The present study was conducted to determine the contribution of nitric oxide to angiotensin II (Ang II) reactivity of afferent and efferent arterioles from Ang II-infused hypertensive rats. Experiments were performed in vitro with the blood-perfused juxtamedullary nephron technique in kidneys harvested from hypertensive Sprague-Dawley rats (181+/-1 mm Hg) that had received 60 ng/min Ang II sub...
متن کاملاثر آنژیوتانسین II در هسته پاراونتریکولار در تشدیدآسیب ایسکمی- پرفیوژن مجدد کلیه
Background: The renal sympathetic nerve activity (RSNA) is enhanced in renal failure. Paraventricular nucleus in hypothalamus is an important central site to regulate sympathetic activity. There are angiotensin II (Ang) II receptors in this nucleus. The aim of this study was to evaluate the effects of angiotensin II in hypothalamic paraventricular nucleus (PVN) on renal ischemia-reperfusion inj...
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تاریخ انتشار 2005